Reductive metabolism of the hypoxia marker pimonidazole is regulated by oxygen tension independent of the pyridine nucleotide redox state
Open Access
- 1 May 1998
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 253 (3) , 743-750
- https://doi.org/10.1046/j.1432-1327.1998.2530743.x
Abstract
2‐Nitroimidazoles, such as pimonidazole, are reduced in cells with low oxygen tension and are, therefore, used as hypoxia markers. However, the effect of the pyridine nucleotide redox state on pimoni...Keywords
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