The estimation of population pharmacokinetic parameters using an EM algorithm
- 1 September 1993
- journal article
- Published by Elsevier in Computer Methods and Programs in Biomedicine
- Vol. 41 (1) , 9-16
- https://doi.org/10.1016/0169-2607(93)90062-p
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- Building population pharmacokineticpharmacodynamic models. I. Models for covariate effectsJournal of Pharmacokinetics and Biopharmaceutics, 1992
- A population analysis of the pharmacokinetics and pharmacodynamics of midazolam in the ratJournal of Pharmacokinetics and Biopharmaceutics, 1991
- Nonlinear Mixed Effects Models for Repeated Measures DataPublished by JSTOR ,1990
- An alternative two stage method via the EM-algorithm for the estimation of population pharmacokinetic parameters.Journal of Pharmacobio-Dynamics, 1988
- Maximum Likelihood Computations with Repeated Measures: Application of the EM AlgorithmJournal of the American Statistical Association, 1987
- A maximum likelihood estimation method for random coefficient regression modelsBiometrika, 1986
- Food and Drug Administration's Guidelines for Clinical Testing of Drugs in the ElderlyDrug Information Journal, 1985
- Alternative Approaches to Estimation of Population Pharmacokinetic Parameters: Comparison with the Nonlinear Mixed-Effect ModelDrug Metabolism Reviews, 1984
- Random-Effects Models for Longitudinal DataPublished by JSTOR ,1982
- Maximum Likelihood Approaches to Variance Component Estimation and to Related ProblemsJournal of the American Statistical Association, 1977