Comprehensive head and neck oncology health status assessment

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Abstract
Background. This article presents the validation of the Head and Neck Cancer Inventory (HNCI), a health status assessment instrument with a small number of multiple‐item domains that captures patients' ratings of functional status and attitude about that function. Methods. The HNCI was administered to patients with upper aerodigestive tract carcinoma. An initial, cross‐sectional study assessed feasibility and reliability. A subsequent, longitudinal study's factor analysis identified ineffective items and confirmed domain cohesiveness. Construct and criterion‐related validity and sensitivity to detect change across time were evaluated. Results. The HNCI was highly reliable. Criterion‐related validity was demonstrated through comparisons with other HNC‐specific instruments. Construct validity was demonstrated based on significant differences between patient groups (HNC/non‐HNC, employment status, clinical stage, and type of treatment). Domain scores were sensitive to change across time. The domains' functional and attitudinal scores were significantly different. Conclusions. The HNCI is a reliable, valid instrument that evaluates the functional and attitudinal components of health status in HNC patients. This survey is recommended for self‐reported health status evaluation in HNC clinical trials. © 2003 Wiley Periodicals, Inc. Head Neck 25: 561–575, 2003