15N NMR substituent effects in pyridines and pyrimidines
- 1 January 1981
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Chemistry
- Vol. 15 (1) , 106-109
- https://doi.org/10.1002/mrc.1270150124
Abstract
15N chemical shifts of 32 substituted pyridines and 19 substituted pyrimidines, together with additional data from the literature, are used to evalute substituent increments, Ai and Aik, in the respective series. Differential chemical shifts, Δδ(N), correlate with corresponding Δδ(C) values whereby, on the ppm scale, nitrogen shifts are approximately three times more sensitive towards substituents than carbon shifts. The 15N increments have proven additive and useful for assignment purposes.Keywords
This publication has 8 references indexed in Scilit:
- 15N‐NMR. Studies of Aminopyridines, Aminopyrimidines and of Some Diazine N‐OxidesHelvetica Chimica Acta, 1980
- 13C substituent effects in monosubstituted benzenesMagnetic Resonance in Chemistry, 1979
- Effects of solvent, protonation, and N-alkylation on the nitrogen-15 chemical shifts of pyridine and related compoundsJournal of the American Chemical Society, 1978
- Natural-abundance nitrogen-15 nuclear magnetic resonance spectroscopy. Nitrogen chemical shifts of alkylpyridines, picolinium, and lutidinium ions, and picoline N-oxidesThe Journal of Physical Chemistry, 1978
- Nitrogen‐14 indor spectra of some 2‐substituted pyrimidinesBulletin des Sociétés Chimiques Belges, 1978
- Nitrogen-15 nuclear magnetic resonance spectroscopy of some nucleosides and nucleotidesJournal of the American Chemical Society, 1977
- Carbon-13 Nuclear Magnetic Resonance Spectra of Some Substituted Benzenes and Additivity of Substituent Effects on Carbon-13 Chemical ShiftsNIPPON KAGAKU KAISHI, 1973
- Nitrogen NMRPublished by Springer Nature ,1973