Immune Thrombocytopenia Induced by Cotrimoxazole
- 1 February 1980
- journal article
- case report
- Published by Wiley in Australian and New Zealand Journal of Medicine
- Vol. 10 (1) , 54-55
- https://doi.org/10.1111/j.1445-5994.1980.tb03420.x
Abstract
Summary: Immune thrombocytopenia induced by cotrimoxazole. A. L. Barr and M. Whineray. Aust. N.Z. J. Med., 1980, 10, pp. 54–55.Cotrimoxazole administration is occasionally associated with thrombocytopenia. Interference with folate metabolism has been postulated.2 The drug has also been postulated to induce an autoantibody by acting as a hapten3, but proof has not been forthcoming. A case is reported in which the serum has been shown to contain an anti‐platelet autoantibody requiring sulphamethoxazole or cotrimoxazole for activity.Keywords
This publication has 4 references indexed in Scilit:
- Acute Pancytopenia Due to Megaloblastic Arrest in Association with Co‐TrimoxazoleThe Medical Journal of Australia, 1978
- Platelet Antibodies in Thrombocytopenic PatientsBritish Journal of Haematology, 1977
- Anti-platelet Antibody Determination by Platelet Factor 3 AssayAmerican Journal of Clinical Pathology, 1976