L-Dopa-Induced Asterixis
- 1 December 1985
- journal article
- research article
- Published by Wiley in Psychiatry and Clinical Neurosciences
- Vol. 39 (4) , 507-513
- https://doi.org/10.1111/j.1440-1819.1985.tb00804.x
Abstract
Three cases with the occurrence of asterixis during the administration of L-dopa were reported. Liver and metabolic functions were normal in all the patients. Upon the appearance of asterixis no other involuntary movements probably resulting from an excess administration of L-dopa were observed. Asterixis occurred accompanied by clinical symptoms such as hallucination and a mild clouding of consciousness by insomnia. Because of its reversal with drug withdrawal, asterixis seemed to be L-dopa-related. The biochemical basis of asterixis is not known but may involve the dopaminergic or serotonergic system.Keywords
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