PRODUCTION OF THE MATERNAL PLACENTA IN RABBITS FOLLOWING ASPIRATION OF CONCEPTUSES

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Abstract
The induction of a decidual cell response in the rabbit uterus has been studied by numerous investigators since its discovery by Loeb (1908). Such a response results from traumatizing the uterine endometrium of pseudopregnant does or the sterile horn of unilaterally pregnant does by means of incisions (Loeb, 1908) or the insertion of threads (Courrier & Kehl, 1930). A similar result is obtained using either thread trauma or the instillation of various chemical stimuli into the uterine lumen of ovariectomized oestrogen-progesterone-maintained does (Elton, 1966). Traumatic deciduomata in rabbits bear little resemblance to the decidua of a normal pregnancy with respect to gross morphology and size, although the same histological change, i.e. decidual cell response, occurs in both. Quantification of such deciduomal masses is difficult, perhaps the optimal criterion being that of glycogen content

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