KINETIC STUDIES OF CORTISOL AND SYNTHETIC CORTICOSTEROIDS IN MAN
- 1 January 1972
- journal article
- Published by Wiley in Clinical Endocrinology
- Vol. 1 (1) , 65-72
- https://doi.org/10.1111/j.1365-2265.1972.tb00378.x
Abstract
SUMMARY: Following the rapid intravenous injection of corticosteroids (cortisol, prednisolone, betamethasone and betamethasone‐17‐valerate), the blood levels of each were estimated and the results analysed in a two‐compartment open model. The kinetic analysis revealed differences in distribution and elimination which could have important therapeuticimplications. A theory is presented for the marked differences seen, and the therapeutic importance of these is discussed.This publication has 16 references indexed in Scilit:
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