Determination of creatinine in human serum. Statistical intercalibration of methods
- 1 January 1995
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in The Analyst
- Vol. 120 (1) , 47-51
- https://doi.org/10.1039/an9952000047
Abstract
An intercalibration of methods was performed in the determination of creatinine in human plasma. Jaffè, enzymatic creatinine-deaminase (CRDI) and ion-interaction reagent high-performance liquid chromatography (HPLC) methods were employed and the results were compared using a parametric t-test for multiple samples and non-parametric Mann–Whitney, Wilcoxon and Friedman tests. The comparison did not show a statistically significant difference in the use of the three methods. The ion-interaction HPLC procedure is proposed as a reference method for creatinine assays.Keywords
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