INHIBITION OF TARGET-CELL MITOSIS AS A MEASURE OF CYTOSTATIC EFFECTS OF ACTIVATED MACROPHAGES ON TUMOR TARGET-CELLS
- 1 January 1977
- journal article
- research article
- Vol. 37 (11) , 3912-3916
Abstract
Studies were done in vitro showing that activated macrophages inhibited mouse EMT-6 mammary tumor target cells from undergoing mitosis. With the use of target cells synchronized in the mitosis phase of the cell cycle, this manifestation of macrophage-mediated cytostatic effects was preceded by the complete inhibition of target cell DNA synthesis as measured by incorporation of [3H]thymidine.This publication has 4 references indexed in Scilit:
- Inhibition of 125IUdR incorporation by supernatants from macrophage and lymphocyte cultures: A cautionary noteCellular Immunology, 1976
- The effects of activated macrophages on tumor target cells: Escape from cytostasisCellular Immunology, 1976
- EFFECTS OF CORYNEBACTERIUM-PARVUM TREATMENT AND TOXOPLASMA-GONDII INFECTION ON MACROPHAGE-MEDIATED CYTOSTASIS OF TUMOR TARGET-CELLS1976
- Growth and nucleic acid synthesis in synchronously dividing populations of HeLa cellsExperimental Cell Research, 1963