Inhibition of HIV-1 replication and syncytium formation by synthetic CD4 peptides
- 1 March 1989
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 105 (1-2) , 129-135
- https://doi.org/10.1007/bf01311123
Abstract
Summary Only one peptide of CD4 (amino acid residues 70–132) among 16 synthetic peptide fragments selectively inhibited HIV-1 replication and HIV-1-induced syncytium formation. Several smaller peptides within this region did not show any activity, except for the peptide (86–132) which showed somewhat lower activity.Keywords
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