The effects of inhibition of fatty acid oxidation in suckling newborn rats
- 15 September 1977
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 166 (3) , 631-634
- https://doi.org/10.1042/bj1660631
Abstract
Inhibition of fatty acid oxidation with pent-4-enoate in suckling newborn rats caused a fall in blood [glucose] and blood [ketone bodies] and inhibition of gluconeogenesis from lactate. Glucose utilization was not increased in newborn rats injected with pent-4-enoate. Active fatty acid oxidation appears to be essential to support gluconeogenesis and to maintain normal blood [glucose] in suckling newborn rats.This publication has 19 references indexed in Scilit:
- Evidence that Fatty Acid Oxidation Stimulates Gluconeogenesis in Newborn RatsBiochemical Society Transactions, 1977
- The effects of inhibition of gluconeogenesis in suckling newborn ratsBiochemical Journal, 1977
- Hormonal control of [14C]glucose synthesis from [U-14C]dihydroxyacetone and glycerol in isolated rat hepatocytesJournal of Biological Chemistry, 1976
- Effects of exogenous hormones and glucose on plasma levels and hepatic metabolism of amino acids in the fetus and in the newborn ratDiabetologia, 1976
- Fuels, Hormones, and Liver Metabolism at Term and during the Early Postnatal Period in the RatJournal of Clinical Investigation, 1973
- Gluconeogenesis in the newborn rat: the substrates and their quantitative significance.1973
- Alanine and Gluconeogenesis in Man: Effect of EthanolJournal of Clinical Endocrinology & Metabolism, 1972
- Inhibition of hepatic gluconeogenesis and fatty acid oxidation by pent-4-enoic acidAmerican Journal of Physiology-Legacy Content, 1970
- Control factors affecting gluconeogenesis in perfused rat liver. Effects of 4-pentenoic acid.1970
- The Physical and Chemical Characterization of Rat’s MilkJournal of Nutrition, 1954