Maternally Derived Immunity to Canine Parvovirus Infection: Transfer, Decline, and Interference with Vaccination
Open Access
- 1 January 1982
- journal article
- Published by American Veterinary Medical Association (AVMA) in Journal of the American Veterinary Medical Association
- Vol. 180 (1) , 37-42
- https://doi.org/10.2460/javma.1982.180.01.37
Abstract
SUMMARY: Antibody to canine parvovirus (cpv) was transferred from an immune bitch to her pups through the placenta and colostrum. Colostral transfer accounted for approximately 90% of the maternally-derived cpvantibody. After suckling, pups had hemagglutination-inhibition titers that averaged 50% of their dam's titer. Maternally derived cpv antibody declined with a half-life of 9.7 days. Pups with hemagglutination-inhibition titers ≥1:80 were immune to oronasal challenge with virulent cpv, but any detectable hemagglutination-inhibition antibody (titer ≥1:10) interfered with active immunization by modified-live feline panleukopenia virus, inactivated feline panleukopenia virus, or inactivated cpv vaccines.This publication has 0 references indexed in Scilit: