In Vitro Uptake and Metabolism of [3H]Indole Compounds in the Pineal Organ of the Pike. II. A Radioautographic Study
- 1 October 1985
- journal article
- research article
- Published by Wiley in Journal of Pineal Research
- Vol. 2 (4) , 357-373
- https://doi.org/10.1111/j.1600-079x.1985.tb00716.x
Abstract
In a previous radiobiochemical study [Falcón et al., 1985] it was demonstrated that the pineal organ of the pike incubated in vitro takes up and metabolizes [3H]serotonin and [3H]melatonin. Parallel to this experiment (present work), pineal organs were investigated by use of light and electron microscopic radioautography to investigate the cell types involved in indole metabolism. Irrespective of the tracer and experimental conditions used, the radioautographic reactions were mainly found in cone-like and modified photoreceptor cells of the pineal parenchyma. Taking into account the limits of the method used as well as previous data concerning (1) the direct photosensitivity of the organ, (2) the focalization of exogenous indoles, and (3) the localization and circadian variations of endogenous ones, it is concluded that the photoperiodic information is translated into both nervous and indolic signals in cone-like photoreceptor cells and into indolic signals in modified photoreceptor cells.Keywords
This publication has 22 references indexed in Scilit:
- Retention of indoles in the pineal organ of the bird (Melopsittacus undulatus, Shaw) during its preparation for radioautographic studyBiology of the Cell, 1984
- Photosensitivity and Biosynthesis of Indole Compounds in the Cells of the Receptor Line of the Pineal Organ of the PikeOphthalmic Research, 1984
- Immunocytochemical localization of serotonin at the ultrastructural level.Journal of Histochemistry & Cytochemistry, 1982
- L'organe pinéal du Brochet (Esox lucius, L.). IV. Sérotonine endogène et activité monoamine oxydasique ; étude histochimique, ultracytochimique et pharmacologiqueReproduction Nutrition Développement, 1980
- STORAGE OF SEROTONIN AND SEROTONIN BINDING PROTEIN IN SYNAPTIC VESICLESJournal of Neurochemistry, 1979
- L'organe pinéal du Brochet (Esox lucius L.). III. Voies intrapinéales de conduction des messages photosensorielsAnnales de Biologie Animale Biochimie Biophysique, 1979
- L'organe pinéal du Brochet (Esox lucius, L.). II. Etude en microscopie électronique de la différenciation et de la rudimentation partielle des photorécepteurs ; conséquences possibles sur l'élaboration des messages photosensorielsAnnales de Biologie Animale Biochimie Biophysique, 1979
- L'organe pinéal du Brochet (Esox lucius, L.). I. Etude anatomique et cytologiqueAnnales de Biologie Animale Biochimie Biophysique, 1979
- Sensory and Glandular Elements of the Pineal OrganPublished by Wiley ,1971
- Differentiation and Regression of the Cells of the Sensory Line in the Epiphysis CerebriPublished by Wiley ,1971