INCREASE OF SISTER CHROMATID EXCHANGES, FOLLOWING TUMOR GRAFTS, IN DIFFERENT IMMUNOCOMPETENT HOSTS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 289  (13) , 923-926
Abstract
Sister chromatid exchange (SCE) frequency of inbred rat or nu/nu mouse bone marrow cells, following tumor grafts, were measured. Increase of SCE was observed in hosts with or without metastases, and with reduced survival rates after malignant tumor grafts. A remote control of tumoral tissue by a diffusion effect was suggested.

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