Accumulation of Mepivacaine Hydrochloride during Caudal Block

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Abstract
Gas chromatography was used to study blood levels of mepivacaine in 5 cases of vaginal delivery in which continuous caudal block was employed as the anesthetic technique. All 5 cases showed a statistically significant increase in the blood levels of mepivacaine with each refill dose. Mepivacaine crossed the placental barrier but did not depress the neonate.