Stereoselective Total Synthesis of (3R,8S)-Falcarindiol, a Common Polyacetylenic Compound from Umbellifers
- 11 March 1999
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 62 (4) , 626-628
- https://doi.org/10.1021/np980418z
Abstract
The first stereoselective total synthesis of (3R,8S)-falcarindiol (1) from l-tartaric acid and d-xylose is reported, via the Cadiot−Chodkiczwicz reaction, to couple 1-bromoalkyne (2) with 3(R)-(tert-butyldiphenylsilyloxy)-1-penten-4-yne (3).Keywords
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