Abstract
The influence of genes in the cytoplasm as revealed by genetics shows that in the final analysis all known types of inheritance can be traced to genes. Whether there are other kinds of inheritance through cytoplasm alone is left open for the future. Inheritance that can be traced to cytoplasmic plastids is admitted on sufficient evidence in a few cases. Some of the practical applications of genetics to the study of physiological processes are described. A few typical cases of the relation of environment to genetics are discussed. The history of the role of enzymes as genetic factors is traced. The theory that genes are enzymes is rejected, but the plausibility of the theory that the genes may be instrumental in the production of enzymes or of other catalysts is admitted on purely theoretical grounds.

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