Isolation and characterization of the components of the sodium pump
- 1 May 1974
- journal article
- research article
- Published by Cambridge University Press (CUP) in Quarterly Reviews of Biophysics
- Vol. 7 (2) , 239-274
- https://doi.org/10.1017/s0033583500001426
Abstract
A satisfactory understanding of the functions of the sodium pump, the system responsible for the active transport of sodium and potassium, require the isolation and characterization of its protein and lipid components which are integrated in the structure of the cell membrane. The enzyme system (Na+ + K+)-ATPase, is located in membrane fragments and behaves in the test tube like the transport system in the intact cell membrane (Skou,1957) Purified preparations of this enzyme will contain some, if not all, of the components of the sodium pump.Keywords
This publication has 133 references indexed in Scilit:
- A study on the influence of the concentration of Mg2+, Pi, K+, Na+, and tris on (Mg2+ + Pi)-supported g-strophanthin binding to (Na+ + K+)-activated ATPase from ox brainBiochimica et Biophysica Acta (BBA) - Biomembranes, 1973
- Antibodies to pig kidney (Na++K+)-ATPase inhibit the Na+ pump in human red cells provided they have access to the inner surface of the cell membraneBiochimica et Biophysica Acta (BBA) - Biomembranes, 1973
- Na+,K+-ATPase complex: Effects of anticomplex antibody on the partial reactions catalyzed by the complexBiochemical and Biophysical Research Communications, 1972
- The phosphorylation and isolation of two erythrocyte membrane proteins in, vitroBiochemical and Biophysical Research Communications, 1972
- The role of aldosterone in the regulation of (Na+ + K+)-ATPase in rat kidneyJournal of Steroid Biochemistry, 1972
- Phosphorylation of a purified (Na++K+) adenosine triphosphataseBiochemical and Biophysical Research Communications, 1971
- The relationship between g-strophanthin-binding capacity and ATPase activity in plasma-membrane fragments from ox brainBiochimica et Biophysica Acta (BBA) - Biomembranes, 1971
- Preparation of highly active (Na+ + K+)-ATPase from the outer medulla of rabbit kidneyBiochemical and Biophysical Research Communications, 1969
- Molecular weight of Na, K-ATPase approximated by the radiation inactivation methodBiochemical and Biophysical Research Communications, 1967
- Lipid-free soluble cytochrome oxidase purification, properties and reaction characteristicsBiochemical and Biophysical Research Communications, 1966