Alimentary Excretion of Phosphorus32 in Rats on High Molybdenum and Copper Diets

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Abstract
The excretion of intramuscularly administered P32 into the tissues and contents of the stomach, duodenum, ileum, jejunum, cecum, and colon of 4 groups of rats on rations containing Mo and Cu at levels of 80–35, 0–35, 80–0, and 0–0 p.p.m., respectively, was determined at intervals ranging from 0.5 to 168 hours after administration, as well as fecal and urinary excretion rates. The results were calculated as per cent dose and per cent dose per milligram of total phosphorus. The group which was fed the high levels of both Mo and Cu excreted less of the isotope into the contents of the various alimentary segments than the other three groups, which were essentially equivalent with respect to excretion. Fecal and urinary excretion varied markedly among the 4 groups. The per cent P32 in the feces was 3.05, 4.54, 5.66 and 7.74, and in the urine 12.0, 16.0, 19.3, and 26.0 for the high Cu-high Mo, high Cu, high Mo, and basal ration rats, respectively, 168 hours after administration.

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