Relapse in recurrent unipolar depression

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Abstract
Treatment of the acute phase of recurrent depression has become both routine and successful in the last decade, but the rates of relapse and recurrence remain a problem. In this study a combined psychopharmacologic/psychotherapeutic approach to the acute and continuation treatment of unipolar depressed patients was used. For 59 patients who completed the continuation phase of treatment, the relapse rate after 8 weeks of recovery was 8.5%. Since other recent studies of recurrent depression have reported relapse rates of 15%-22%, these results suggest that there are advantages in combined treatment.

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