MENINGOCOCCUS ENDOCARDITIS, WITH SEPTICEMIA

1 July 1911

journal article
research article
Published by American Medical Association (AMA) in Archives of internal medicine (1908)

Vol. VIII (1) , 1-16
https://doi.org/10.1001/archinte.1911.00060070006001

Abstract

Meningococcus septicemia was first reported by Gwyn¹in 1899. The case was one of epidemic meningitis complicated by acute arthritis. The meningococcus was isolated from the spinal fluid, synovial fluid, and the blood. Cochez and Lemaire²in 1901 were able to demonstrate the meningococcus in the blood of two meningitis patients. Jakobitz,³Martini and Rohde,⁴Lenhartz,⁵Marcovitch,⁶Robinson,⁷and Duval⁸have since made similar reports, the septicemia in all these cases being associated with meningitis. Elser,⁹examining the blood in forty-one cases of cerebrospinal meningitis, found the meningococcus in ten, or about 25 per cent. It has been observed that in most instances where the meningococcus has been found in the circulating blood, the disease has been fatal, and some form of extrameningeal lesion has been present. The endothelial-lined cavities, such as the joints, pleura, pericardium and endocardium have been the sites of these complicating

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