Erythema palmare hereditarium is the name that was given by Lane1 in 1929 to a condition he observed in 2 men. Both had had red palms as long as they could remember, and other members of their families presented similar changes. The condition was characterized by bright erythema of the palms which was sharply limited at the wrist line and along the sides of the hands. In one of the patients the redness extended onto the dorsa of the terminal phalanges. There were no other changes in the skin and no subjective symptoms. Since this first description only 9 other cases have been reported, although the condition is probably not rare, as was brought out in the discussion of Lane's paper. During the past two years we have seen 9 patients with palmar erythema, all of whom were women. In 4 the condition occurred during pregnancy and was associated