A SUMMARY OF THE FINDINGS IN 1100 GLUCOSE TOLERANCE ESTIMATIONS*

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Abstract
From an analysis of a series of 1100 glucose tolerance tests (using 100 gm. of glucose by mouth), the author concludes the following: We can draw the following conclusions: Patients with glycosuria are not all diabetics. About 2/3 are non-diabetic and 1/3 are diabetic, a finding which indicates the necessity of investigating each case carefully to determine its exact status. When glycosuria occurs in pregnancy it is important to study the case carefully as the incidence of diabetes in this group is not insignificant. The discovery of glycosuria in an examination for life insurance often leads to unfair discrimination. In my series shown in Table I, 62.2% of such cases were non-diabetic. These subjects are perfect life insurance risks. Hyperglycemia in a routine examination (21/2 hrs. or more after a meal or during fasting), even though slight, should not be disregarded, for in my series 40% of such cases were diabetic. When there is diabetic history in the family the diabetic incidence is higher than otherwise. Obesity carries a high incidence of diabetes, to say nothing of other evils. Normal or subnormal weight protects the individual against diabetes more than any other single factor. It means that the individual eats moderately and that but a small load is thrown on the insulogenic function of the pancreas. Glycosuria in the presence of hyperthyroidism carries with it a high incidence of diabetes, and should not be ignored. The problems presented by such cases should be rigidly investigated. Hypothy-roidism is the reverse of hyperthyroidism and the incidence of diabetes among subjects of hypothyroidism is slight. Acromegaly carries with it a high diabetic incidence. Hypopituitarism carries with it a low incidence of diabetes. Hypertension carries with it a high diabetic incidence. Tuberculosis (glycosuria), arthritis, carcinoma and syphilis carry with them a high diabetic incidence. Skin diseases carry with them low diabetic incidence. Diabetes occurred in 29.9% of patients under 20 years of age, these cases having been investigated because of their glycosuria.

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