PATHOLOGICAL STUDY ON THE CHANGES OF LYMPHATIC TISSUES IN SHOCK WITH SPECIAL REFERENCE TO SECONDARY NODULE LESIONS

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Abstract
The present authors carried out a pathological study on the changes in the lymphatic tissues of 38 autopsy cases associated with fatal shock. As a result, they confirmed that; (1) the microscopic lesion characterized by prominent destruction of the constituent cells of the secondary nodules appeared systematically in the lymphatic tissues of various regions, added by other occasional changes, such as coagulation necrosis, hemorrhages and transudation; (2) there occurred also marked atrophy of the secondary nodules in the cases with long duration of mild shock, or in those with temporary recovery from severe shock; and (3) the cellular destruction of the secondary nodules was closely correlated with the duration and severity of shock.