REQUIREMENT OF DIVALENT METAL IONS FOR BACITRACIN ACTIVITY
- 31 May 1962
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 83 (6) , 1315-+
- https://doi.org/10.1128/jb.83.6.1315-1317.1962
Abstract
The antibiotic activity of bacitracin towards Staphylococcus aureus is completely suppressed by ethylenediaminetetraacetate. The conclusion that bacitracin activity requires the presence of metal ions is supported by the demonstration that the addition of a number of divalent ions reverses the effect of ethylenediaminetetraacetate. The most active of these ions, cadmium, manganese, and zinc, directly enhance the activity of bacitracin.Keywords
This publication has 3 references indexed in Scilit:
- Enhancement of bacitracin by the metallic ions of group II B.1958
- The assay of bacitracinJournal of the American Pharmaceutical Association (Scientific ed.), 1948
- Bacitracin: A New Antibiotic Produced by a Member of the B. subtilis GroupScience, 1945