Pseudomembranous Colitis with Recurring Diarrhoea and Prolonged Persistence of Clostridium Difficile in A 10‐Year‐Old Girl

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Abstract
A 10‐year‐old girl developed, after treatment with amyxocillin, a clinically and sigmoidoscopi‐cally apparent pseudomembranous colitis with positive Clostridium difficile stool culture. Treatment with vancomycin resulted in rapid clinical cure, but there was a relapse of diarrhoea and reappearance of C. difficile, with no pseudomembranous colitis, within one month. Clinical symptoms subsided spontaneously but C. difficile persisted for 2 more months in the stools. This case reflects three different aspects of C. difficile infection in one child: pseudomembranous colitis, ordinary diarrhoea, and symptomless carrier state.