The use of low-dose trazodone in the treatment of painful diabetic neuropathy
- 1 September 1999
- journal article
- Published by American Podiatric Medical Association in Journal of the American Podiatric Medical Association
- Vol. 89 (9) , 468-471
- https://doi.org/10.7547/87507315-89-9-468
Abstract
Thirty-one adult diabetic patients with painful distal symmetrical polyneuropathy were treated with low doses of oral trazodone (50 or 100 mg/day). After 2 weeks of therapy, 19 patients (61.3%) experienced symptomatic relief, and 7 (22.6%) experienced complete relief. Although 8 patients (25.8%) discontinued the drug because of side effects, these were relatively minor (dizziness, headache, insomnia). Low-dose trazodone is recommended as an effective treatment option for painful diabetic neuropathy.Keywords
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