Interlaboratory Bilirubin Variability
- 1 March 1982
- journal article
- research article
- Published by American Academy of Pediatrics (AAP) in Pediatrics
- Vol. 69 (3) , 277-281
- https://doi.org/10.1542/peds.69.3.277
Abstract
Stabilized liquid quality control sera, some with elevated bilirubin concentrations, were distributed to laboratories for total and conjugated (direct) bilirubin analyses. Interlaboratory variability was high; for example, results ranged from 10.9 to 24.0 mg/100 ml for a serum with a mean bilirubin concentration of 18.1 mg/ 100 ml. Coefficients of variation were typically 10% to 12% for total bilirubin and approximately 24% for conjugated bilirubin analyses. It is believed that these stabilized sera, when used as quality control materials, can help reduce the unacceptably large interlaboratory variability found in this study.Keywords
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