Selective Pancreatic Enzyme Secretion due to a New Peptide Called Chymodenin
- 15 March 1974
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 183 (4129) , 1087-1089
- https://doi.org/10.1126/science.183.4129.1087
Abstract
Chymodenin, a peptide newly isolated from porcine duodenum, elicited a rapid threefold increase in secretion of chymotrypsinogen while increasing secrelion of total protein by only, about 40 percent; lipase secretion was unaffected. The pancreas appears able, under chymodenin stimulation, to rapidly alter the transport of an individual enzyme as opposed to producing en masse secretion of enzyme.Keywords
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