A Succinct Asymmetric Synthesis of (2S,3R)-2-Methyl-3-aminopentanoic Acid Hydrochloride
- 1 January 1994
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1994 (02) , 117-118
- https://doi.org/10.1055/s-1994-22760
Abstract
The highly stereoselective conjugate addition of lithium (R)-(α-methylbenzyl)benzylamide (R)-2 to tert-butyl (E)-2-methyl-2-pentenoate 3 affords a straightforward synthesis of (2S,3R)-2-methyl-3-aminopentanoic acid 1 as its hydrochloride salt 5.Keywords
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