Antidepressants and liver disease
Open Access
- 1 September 1972
- Vol. 13 (9) , 697-701
- https://doi.org/10.1136/gut.13.9.697
Abstract
Patients with cirrhosis were found to be extremely sensitive to tranylcypromine, and the use of this drug for the treatment of depression in such patients is contraindicated. Amitriptyline has a wider margin of safety in such patients, but caution is necessary when the higher therapeutic doses are prescribed.Keywords
This publication has 13 references indexed in Scilit:
- FALSE NEUROTRANSMITTERS AND HEPATIC FAILUREThe Lancet, 1971
- Iatrogenic epilepsy due to antidepressant drugsBMJ, 1969
- Effects of Chlorpromazine in Patients with Hepatic DiseaseBMJ, 1969
- ENCEPHALOPATHY AFTER PORTACAVAL ANASTOMOSISThe Lancet, 1968
- INTERACTION BETWEEN CHEESE AND MONOAMINE-OXIDASE INHIBITORS IN RATS AND CATSThe Lancet, 1964
- QUANTITATIVE ELECTROENCEPHALOGRAPHY IN MAN AS A MEASURE OF CNS STIMULATION*Annals of the New York Academy of Sciences, 1963
- EFFECT OF AMITRIPTYLINE ON EEG1962
- Amines in blood and urine in relation to liver diseaseClinica Chimica Acta; International Journal of Clinical Chemistry, 1961
- THE EFFECT OF THE AMINE OXIDASE INHIBITOR MARSILID ON AMMONIUM METABOLISM IN LIVER DISEASE1958
- METHIONINE TOXICITY IN LIVER DISEASE AND ITS PREVENTION BY CHLORTETRACYCLINE1956