Vitamin C Therapy of Advanced Cancer

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To the Editor: This letter is a comment on the paper by Creagan et al.1 entitled, "Failure of High-Dose Vitamin C (Ascorbic Acid) Therapy to Benefit Patients with Advanced Cancer: A Controlled Trial," and the letter by Creagan and Moertel.2 The paper by Creagan et al. misrepresents the Vale of Leven study3 4 5 6 in stating that 50 of the 100 ascorbate-treated patients, rather than only four, had received prior chemotherapy.Answering a letter from me, Dr. Moertel wrote on May 6, 1977, "I feel it is essential in our first evaluation of ascorbic acid that we make every effort to duplicate . . .