RESPONSE OF CHOROIDAL AND CEREBRAL CIRCULATIONS TO CHANGING ARTERIAL PCO2 AND ACETAZOLAMIDE IN BABOON

  • 1 January 1977
    • journal article
    • research article
    • Vol. 16  (6) , 576-580
Abstract
Having established control values for choroidal and cerebral blood flow in 12 baboons, the response of both circulations to changing arterial [partial CO2 pressure] and i.v. acetazolamide was studied. The blood flow in both circulations varied directly with the PACO2 [arterial CO2 pressure] the magnitude of the response being very similar. There was a 3.6% change in both choroidal and cerebral blood flow per millimeter of HG change in PACO2. I.v. acetazolamide (25 mg/kg) produced an increase in flow lasting approximately 50 min in both cerebral and choroidal circulations.

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