Voriconazole‐Induced Retinoid‐Like Photosensitivity in Children
- 30 November 2004
- journal article
- case report
- Published by Wiley in Pediatric Dermatology
- Vol. 21 (6) , 675-678
- https://doi.org/10.1111/j.0736-8046.2004.21614.x
Abstract
Abstract: Voriconazole is a new triazole antifungal agent with activity against a wide range of systemic fungal pathogens, including Aspergillus spp. Photosensitivity is a rarely reported side effect of voriconazole, hypothesized to be a result of retinoid‐like effects. We report two children with chronic granulomatous disease to whom voriconazole was administered for chronic invasive aspergillosis. Severe photosensitivity occurred in both patients, one of whom had striking photodamage at the 5‐month follow‐up.Keywords
This publication has 23 references indexed in Scilit:
- Muco-cutaneous retinoid-effects and facial erythema related to the novel triazole antifungal agent voriconazoleClinical and Experimental Dermatology, 2001
- New investigational antifungal agents for treating invasive fungal infectionsExpert Opinion on Investigational Drugs, 2000
- Aspergillosis in Children with Cancer: A 34-Year ExperienceClinical Infectious Diseases, 1999
- Antifungal Agents in the 1990sDrugs, 1997
- Human skin levels of retinoic acid and cytochrome P-450-derived 4-hydroxyretinoic acid after topical application of retinoic acid in vivo compared to concentrations required to stimulate retinoic acid receptor-mediated transcription in vitro.Journal of Clinical Investigation, 1992
- Discoid lupus erythematosus-like lesions in carriers of X-linked chronic granulomatous diseaseBritish Journal of Dermatology, 1992
- Severe photodermatitis during ketoconazole therapyClinical and Experimental Dermatology, 1988
- The RetinoidsDrugs, 1987
- Discoid lupus erythematosus‐like skin lesions in a patient with autosomal recessive chronic granulomatous diseaseClinical Genetics, 1986
- KetoconazoleDrugs, 1982