SYNTHESIS OF DITHIO-, THIO-AND CARBAMOYL ESTER DERIVATIVES OF MONOSACCHARIDES AND ITOLS
- 1 January 1998
- journal article
- research article
- Published by Taylor & Francis in Phosphorus, Sulfur, and Silicon and the Related Elements
- Vol. 133 (1) , 41-59
- https://doi.org/10.1080/10426509808032452
Abstract
Regiospecific carbamoylation of O-isopropylidene protected monosaccharides and itols gave a large range of novel carbamoyl, thiocarbamoyl and dithiocarbamoyl esters. These fully, partially and unprotected carbohydrates possess both modulable hydrophilic character and potential biological properties. Some carbamoyl esters showed, by NMR spectroscopy, characteristics of Z-E isomerism; the rotational energy barrier was higher for the thiocarbamates than for the corresponding carbamates.Keywords
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