Crystal Formation: A New Complication of Total Parenteral Nutrition

1 December 1973

journal article
Published by American Academy of Pediatrics (AAP) in Pediatrics

Vol. 52 (6) , 864-866
https://doi.org/10.1542/peds.52.6.864

Abstract

Since 1971, the Newborn Intensive Care Unit (NICU) of the Charleston Area Medical Center has developed considerable experience with Total Parenteral Nutrition (TPN). A new technical complication of this procedure has been encountered and is reported herewith. It is not the purpose of this communication to repeat the background of TPN,¹ or to detail the case histories involved. Initially, like others, we used a mixture containing a casein hydrolysate (5% Amigen and 5% Dextrose Injection*), additional glucose, and minerals including calcium gluconate. In May 1972 we changed our formula to include a fibrin hydrolysate (Aminosol 5% in D5W†). At the same time, we added phosphate ion by changing from potassium chloride to potassium acid phosphate (Table I) .

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