Cancer-Testis Genes Are Coordinately Expressed and Are Markers of Poor Outcome in Non–Small Cell Lung Cancer
Open Access
- 15 November 2005
- journal article
- Published by American Association for Cancer Research (AACR) in Clinical Cancer Research
- Vol. 11 (22) , 8055-8062
- https://doi.org/10.1158/1078-0432.ccr-05-1203
Abstract
Purpose: Cancer-testis genes mapping to the X chromosome have common expression patterns and show similar responses to modulators of epigenetic mechanisms. We asked whether cancer-testis gene expression occurred coordinately, and whether it correlated with variables of disease and clinical outcome of non–small cell lung cancer (NSCLC).Keywords
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This publication has 55 references indexed in Scilit:
- Evolving anticancer drug valproic acid: Insights into the mechanism and clinical studiesMedicinal Research Reviews, 2005
- A Mouse Skin Multistage Carcinogenesis Model Reflects the Aberrant DNA Methylation Patterns of Human TumorsCancer Research, 2004
- DNA methylation in mouse gametogenesisCytogenetic and Genome Research, 2004
- The history of cancer epigeneticsNature Reviews Cancer, 2004
- Tissue Microarray Evaluation of Melanoma Antigen E (MAGE) Tumor-Associated Antigen ExpressionAnnals of Surgery, 2002
- DNA methylation in cancer: too much, but also too littleOncogene, 2002
- Prognostic relevance of MAGE‐A4 tumor antigen expression in transitional cell carcinoma of the urinary bladder: A tissue microarray studyInternational Journal of Cancer, 2002
- A Member of the GAGE Family of Tumor Antigens is an Anti-Apoptotic Gene that Confers Resistance to Fas/CD95/APO-1, Interferon-g, Taxol and g-irradiationCancer Biology & Therapy, 2002
- Expression of MAGE-antigens in normal tissues and cancerInternational Journal of Cancer, 2000
- Aberrant CpG-island methylation has non-random and tumour-type–specific patternsNature Genetics, 2000