Difference between Influences of Homologous and Heterologous Maternal Antibodies on Response to Serotype-2 and Serotype-3 Marek's Disease Vaccines
- 1 January 1981
- journal article
- research article
- Published by JSTOR in Avian Diseases
- Vol. 25 (1) , 74-81
- https://doi.org/10.2307/1589828
Abstract
Marek''s disease (MD) vaccines representing serotypes 2 (SB-1 strain of MD virus) and 3 (FC-126 strain of turkey herpesvirus) were administered to 1 day old MD-susceptible chicks that either were free of antibodies or carried maternally derived antibodies against SB-1, FC-126 or a serotype-1 MD virus, CU-2 strain. Homologous antibodies delayed the development of vaccine virus viremias and inhibited vaccinal immunity, as judged by protection against challenge with the virulent JM-10 strain of MD virus 7 days postvaccination. Heterologous antibodies had little effect on vaccine responses. Antibodies interfered with cell-associated and cell-free vaccine virus.This publication has 1 reference indexed in Scilit:
- Characterization of an Apparently Nononcogenic Marek's Disease Virus23JNCI Journal of the National Cancer Institute, 1978