L-AND-H VARIANTS OF REED-STERNBERG CELLS EXPRESS SIALYLATED LEU M1 ANTIGEN
- 1 February 1986
- journal article
- research article
- Vol. 122 (2) , 199-203
Abstract
Anti-Leu M1 generally does not stain the lymphocytic and histocytic (L and H) variants of Reed-Sternberg cells in the lymphocyte predominant type of Hodgkin''s disease. However, the authors found that after neuraminidase treatment for removal of sialic acid, the L and H cells in more than half of the cases studied could be stained by anti-Leu M1. This result strongly suggests that L and H cells differ from the Reed-Sternberg cells in other types of Hodgkin''s disease in their unique capacity to sialylate the 150-kd Leu M1 antigen.This publication has 17 references indexed in Scilit:
- LEU-M1 - A MARKER FOR REED-STERNBERG CELLS IN HODGKINS-DISEASE - AN IMMUNOPEROXIDASE STUDY OF PARAFFIN-EMBEDDED TISSUES1985
- On the natural biology of the malignant cells in Hodgkin's diseaseInternational Journal of Radiation Oncology*Biology*Physics, 1985
- An immunohistological study of the cellular constituents of Hodgkin's disease using a monoclonal antibody panelHistopathology, 1984
- Production of a monoclonal antibody specific for Hodgkin and Sternberg–Reed cells of Hodgkin's disease and a subset of normal lymphoid cellsNature, 1982
- A monoclonal antibody (MMA) thet identifies a differentiation antigen on human myelomonocytic cellsClinical Immunology and Immunopathology, 1982
- Possible origin of the Reed-Sternberg cell from an interdigitating reticulum cell.1982
- On The Biology and Immunology of Hodgkin’s DiseasePublished by Springer Nature ,1981
- The diversity of the immunohistological staining pattern of Sternberg-Reed cells.Journal of Histochemistry & Cytochemistry, 1980
- Nodular paragranuloma and progressively transformed germinal centersVirchows Archiv B Cell Pathology Including Molecular Pathology, 1979
- Hodgkin's disease with lymphocytic predominance, nodular type (nodular paragranuloma) and progressively transformed germinal centres—a cytohistological studyHistopathology, 1979