Combined Modality Therapy for Localized Hodgkin’s Disease

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Abstract
Some clinical trials indicated that combination therapy with intensive radiation therapy followed by chemotherapy significantly prolongs the disease-free interval of patients with Hodgkin''s disease confined to lymph nodes. The present report updates the results of a small previously published study of combined modality treatment of stages I and II Hodgkin''s disease. Although patients treated with radiation therapy followed by chemotherapy have the longest median complete remission duration, patients treated with radiation alone have a superior survival rate. Follow-up in this study ranges from 34-93 mo. after the completion of all therapy.

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