Synthetic uses of the sequential ring positional reactivity in Pyridin-3-ol and derivatives
- 1 January 1981
- journal article
- research article
- Published by CSIRO Publishing in Australian Journal of Chemistry
- Vol. 34 (4) , 927-932
- https://doi.org/10.1071/ch9810927
Abstract
A series of ring-substituted pyridin-3-ols has been prepared. The key to the scheme is the introduction of a bromo group to a specific ring position as a temporary blocking agent. As well as hydrogenolysis of the bromo function, nucleophilic displacement has also been investigated.Keywords
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