Benign and Malignant Epithelial Tumors of the Rete Testis in Mice

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Abstract
Two papillary cystadenomas and one papillary cystadenocarcinoma in the rete testis were found in two of 500 very old male JCL:ICR mice; the hosts had no other tumors. One mouse had bilateral cystic tumors. A 5 × 3 × 3 mm papillary cystadenoma was observed in the rete of the right testis. A 7 × 3 × 3 mm tumor with a mixed pattern of papillary cystadenocarcinoma and papillotubular adenocarcinoma was found in the rete of the left testis; the latter extended from the mediastinum to the ductuli efferentes and the caput epididymis. The other mouse had a 9 × 5 × 5 mm papillary cystadenoma of borderline malignancy in the rete of the right testis. The mice had no clinical signs.