Soluble Interleukin 6 Receptor
Open Access
- 18 September 2006
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 166 (16) , 1725-1731
- https://doi.org/10.1001/archinte.166.16.1725
Abstract
Sleep-related breathing disorder (SRBD) is characterized by repetitive complete or partial upper airway collapse that occurs during sleep and is often associated with intermittent repetitive hypoxia and cortical arousal. Growing data indicate that SRBD is a risk factor for hypertension, cardiovascular disease (CVD), stroke, and increased mortality.1-4 Sleep-related breathing disorder–associated hypoxia and sympathetic activation may contribute to atherosclerosis by promoting enhanced states of systemic inflammation. Results from a recent observational study suggest that increased CVD events and CVD mortality are high among individuals with untreated moderate to severe SRBD compared with individuals with less severe SRBD.5This publication has 1 reference indexed in Scilit:
- Systemic inflammation in unstable angina is the result of myocardial necrosisJournal of the American College of Cardiology, 2002