IS PLASMA ZINC A USEFUL INVESTIGATION

1 January 1979

journal article
research article

Vol. 49 (4) , 413-418

Abstract

Plasma Zn [human] is totally protein bound and its concentration is markedly influenced by alteration in protein concentration. Venous occlusion such as is used prior to venepuncture causes a marked increase in plasma Zn concentration. The extent of this change exceeds the analytical variation for Zn determination and may cause difficulty in the interpretation of plasma values. Although in most individuals there is a close correlation between plasma Zn and total protein, collectively this is not so, thus adjusting Zn values for change in protein is inappropriate. For plasma Zn to be a useful investigation blood samples should be obtained without venous occlusion.

This publication has 0 references indexed in Scilit: