High Mutation Frequency in Drosophila Pseudoöbscura, Race B
- 1 May 1943
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 29 (5) , 137-144
- https://doi.org/10.1073/pnas.29.5.137
Abstract
Statistical analysis indicates that the increased mutation rate is due to a dominant "Mutator" gene probably located on the 2d chromosome. When heterozygous the rate is increased approx. 34 times, when homozygous approx. 70 times, indicating a linear increase with dosage of Mutator gene. Mutations occur without preference at any time during the development of both germ and somatic lines. Only "visible" sex-linked recessives were used as indicators, of which approx. 2,000 were observed.This publication has 5 references indexed in Scilit:
- A STUDY OF A CASE OF HIGH MUTATION RATE IN DROSOPHILA MELANOGASTERGenetics, 1942
- Female Sterility in Interracial Hybrids of Drosophila PseudoöbscuraProceedings of the National Academy of Sciences, 1941
- High Mutation Frequency Induced by HybridizationProceedings of the National Academy of Sciences, 1939