Mapping Diabetes-Susceptibility Genes: Lessons Learned From Search for DNA Marker for Maturity-Onset Diabetes of the Young
- 1 April 1992
- journal article
- review article
- Published by American Diabetes Association in Diabetes
- Vol. 41 (4) , 401-407
- https://doi.org/10.2337/diab.41.4.401
Abstract
During our search for a marker for non-insulin-dependent diabetes mellitus (NIDDM) in a large multigenerational family with a form of NIDDM termed maturity-onset diabetes of the young (MODY), we learned a great deal that may serve to streamline the search for diabetes-susceptibility genes in other families. We describe here our experience and suggest strategies that may enhance the search for markers for other diabetes susceptibility genes with genetic linkage approaches.Keywords
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