Carcinoembryonic Antigen in Fetal Eccrine Glands: An Immunohistochemical Study
- 1 April 1984
- journal article
- Published by Wiley in Pediatric Dermatology
- Vol. 1 (4) , 281-282
- https://doi.org/10.1111/j.1525-1470.1984.tb01129.x
Abstract
Developing fetal eccrine glands were examined for the presence of carcinoembryonic antigen (CEA) using an unlabeled antibody peroxidase-antiperoxidase technique and rabbit antibody to human CEA. The earliest sign of commitment to the formation of an eccrine gland was the presence of CEA within a single keratinocyte in fetal epidermis. As the eccrine unit evolved, we found CEA in both acrosyringeal cells and the ductal cells. Although the function of CEA in eccrine gland remains undefined, this substance may play an integral role in the earliest development of the gland as well as in its normal function in the adult.Keywords
This publication has 4 references indexed in Scilit:
- Paget'S disease of the skin. A unifying concept of histogenesisCancer, 1982
- Carcinoembryonic antigen in benign sweat gland tumorsArchives of Dermatology, 1982
- Carcinoembryonic antigen present in human eccrine sweatJournal of the American Academy of Dermatology, 1981
- The Ultrastructure of the Skin of Human EmbryosJournal of Investigative Dermatology, 1965