Enzymes in organic synthesis. 40. Evaluation of the enantioselectivity of the pig liver esterase catalyzed hydrolyses of racemic piperidine carboxylic acid esters
- 1 December 1987
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 65 (12) , 2722-2726
- https://doi.org/10.1139/v87-452
Abstract
Pig liver esterase (PLE) catalyzed hydrolysis of racemic piperidine esters proceeds enantioselectively to give product acids and recovered esters in 0-47% enantiomeric excess.This publication has 6 references indexed in Scilit:
- Enzymes in organic synthesis. 35. Stereoselective pig liver esterase catalyzed hydrolyses of 3-substituted glutarate diesters. Optimization of enantiomeric excess via reaction conditions controlThe Journal of Organic Chemistry, 1986
- Asymmetric synthesis of 2-alkyl pyrrolidines and piperidines. Synthesis of (+)-metazocineJournal of the American Chemical Society, 1985
- Enzymes in organic synthesis. 33. Stereoselective pig liver esterase-catalyzed hydrolyses of meso cyclopentyl-, tetrahydrofuranyl-, and tetrahydrothiophenyl-1,3-diestersCanadian Journal of Chemistry, 1985
- Enantioselective hydrolysis of 3-hydroxy-3-methylalkanoic acid esters with pig liver esteraseThe Journal of Organic Chemistry, 1983
- Quantitative analyses of biochemical kinetic resolutions of enantiomersJournal of the American Chemical Society, 1982
- Stereochemical studies on medicinal agents. V. Synthesis, configuration, and pharmacological activity of pipradrol enantiomersJournal of Medicinal Chemistry, 1968