Effects of Propranolol on the Cardiovascular Response to Cyclopropane and Halothane

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Abstract
Five dogs were anesthetized with cyclopropane and five with halothane. Cardiac output, stroke volume, arterial blood pressure, myocardial contractility, myocardial segment length and peripheral resistance were measured before and after the administration of propranolol, 0.2 mg/kg. In the cyclopropane group, peripheral resistance increased, but cardiac output, stroke volume and contractility decreased markedly. Segment length and mean blood pressure were not significantly altered. In the halothane group, the only significant change after propranolol was a decrease in heart rate.

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